| Idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome) and concurrent psychotropic drug administration. | |
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MedLine Citation:
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PMID: 8378413 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gilbert's Syndrome is a benign familial condition in which unconjugated hyperbilirubinemia occurs in the absence of structural liver disease or hemolysis. Phenothiazines and tricyclic medications are often withheld in patients with preexisting liver disease. The authors present four patients with Gilbert's Syndrome and concurrent psychiatric illness. Administration of phenothiazine antipsychotics or tricyclic antidepressants proved beneficial and produced no adverse effects on hepatic function. The authors discuss clinical aspects of Gilbert's Syndrome in psychiatric patients and conclude that phenothiazine antipsychotic medication should not necessarily be withheld from these patients. |
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Authors:
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R Durst; K Jabotinsky-Rubin; A Dorevitch; L Kikinzon; R Tur-Kaspa |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pharmacopsychiatry Volume: 26 ISSN: 0176-3679 ISO Abbreviation: Pharmacopsychiatry Publication Date: 1993 Mar |
Date Detail:
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Created Date: 1993-10-21 Completed Date: 1993-10-21 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8402938 Medline TA: Pharmacopsychiatry Country: GERMANY |
Other Details:
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Languages: eng Pagination: 49-52 Citation Subset: IM |
Affiliation:
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Talbieh Mental Health Center, Jerusalem, Israel. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antidepressive Agents, Tricyclic / therapeutic use* Depressive Disorder / complications, drug therapy Female Fluphenazine / therapeutic use Gilbert Disease / complications*, drug therapy Humans Male Mental Disorders / complications*, drug therapy Middle Aged Paranoid Disorders / complications, drug therapy Phenothiazines / therapeutic use* Schizoid Personality Disorder / complications, drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Antidepressive Agents, Tricyclic; 0/Phenothiazines; 69-23-8/Fluphenazine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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