Document Detail

Idiopathic thrombocytopenic purpura complicating pregnancy.
MedLine Citation:
PMID:  11913994     Owner:  NLM     Status:  MEDLINE    
Idiopathic thrombocytopenic purpura (ITP) is a condition that often develops in young women, and, consequently, physicians will frequently manage pregnant patients with this disorder. The lack of prospective trials investigating ITP in pregnancy has meant that physicians frequently rely on personal experience and anecdotal evidence to manage these patients. However, recent, large, prospective and retrospective studies have clarified several important aspects of ITP in pregnancy. First, ITP should be distinguished from incidental thrombocytopenia of pregnancy, a high frequency and benign, mild drop in the platelet count that occurs late in pregnancy. Second, although the platelet count often drops in pregnant ITP patients, serious morbidity or mortality is distinctly uncommon for the mothers. The overall frequency of thrombocytopenia in the infant is quite low, and about 5% of infants will have a birth platelet count less than 20 x 10(9)/L and about 1% will have significant bleeding complications.
John G Kelton
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Blood reviews     Volume:  16     ISSN:  0268-960X     ISO Abbreviation:  Blood Rev.     Publication Date:  2002 Mar 
Date Detail:
Created Date:  2002-03-26     Completed Date:  2002-08-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8708558     Medline TA:  Blood Rev     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  43-6     Citation Subset:  IM    
Copyright Information:
Copyright 2002, Elsevier Science Ltd. All rights reserved.
Department of Medicine, McMaster University Medical Center, Hamilton, Ontario, Canada.
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MeSH Terms
Delivery, Obstetric
Diagnosis, Differential
Pregnancy Complications, Hematologic / diagnosis*,  epidemiology,  therapy
Purpura, Thrombocytopenic, Idiopathic / diagnosis*,  epidemiology,  therapy
Thrombocytopenia / classification,  etiology

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