Document Detail

Idiopathic supraclinoid and internal carotid bifurcation steno-occlusive disease in young American adults.
MedLine Citation:
PMID:  10552029     Owner:  NLM     Status:  MEDLINE    
We report a series of American adults with idiopathic steno-occlusive disease of the supraclinoid internal carotid artery and its bifurcation. We reviewed the clinical records and imaging of 18 patients, 16 women and 2 men, aged 20-53 years (mean 35 years). There were no predominating risk factors for vascular occlusive disease, such as oral contraceptive use, hypertension, diabetes mellitus, or smoking. Four patients had irregularity of their cervical internal carotid arteries in a pattern not classic but suspicious of fibromuscular dysplasia. Eleven patients met the criteria for moyamoya disease, having both bilateral disease and moyamoya collateral lenticulostriate arteries. Necropsy in one case showed intimal thickening with duplication of the internal elastic lamina involving the internal carotid artery bifurcation bilaterally. We found a marked predominance of young and middle-aged females in our American adults, but our findings do not support the association with birth-control pills previously reported.
H J Cloft; D F Kallmes; R Snider; M E Jensen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neuroradiology     Volume:  41     ISSN:  0028-3940     ISO Abbreviation:  Neuroradiology     Publication Date:  1999 Oct 
Date Detail:
Created Date:  1999-12-14     Completed Date:  1999-12-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1302751     Medline TA:  Neuroradiology     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  772-6     Citation Subset:  IM    
Department of Radiology, Emory University Hospital, 1364 Clifton Rd. N. E., Atlanta, GA 30322, USA.
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MeSH Terms
Age Factors
Arterial Occlusive Diseases / etiology,  pathology,  radiography*
Carotid Artery Diseases / etiology,  pathology,  radiography*
Carotid Artery, Internal / pathology,  radiography
Cerebral Angiography
Contraceptives, Oral / adverse effects
Middle Aged
Moyamoya Disease / pathology,  radiography*
Risk Factors
Reg. No./Substance:
0/Contraceptives, Oral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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