Document Detail

Idiopathic small-intestinal inflammation after colectomy for ulcerative colitis.
MedLine Citation:
PMID:  18467187     Owner:  NLM     Status:  MEDLINE    
BACKGROUND & AIMS: Severe ileostomy dysfunction with high ileostomy volumes or severe diarrhea after panproctocolectomy and restorative ileo-anal pouch formation are a rare but serious development after surgery for ulcerative colitis (UC). The incidence, severity, morbidity, and mortality are poorly documented in the literature. METHODS: We describe the case of a patient who developed life-threatening diarrhea after surgery for UC and review the literature. RESULTS: Eight cases have now been described in the literature. Small-bowel disease has developed up to 17 months after colectomy. Most cases responded to corticosteroid therapy. A single case in which this treatment was delayed was fatal. CONCLUSIONS: This is a rare sequel to colectomy for UC, but one which is serious and can be fatal. If the diagnosis is made promptly, a full response to treatment can be expected and the long-term outlook is excellent.
Ian R Gooding; Roger Springall; Ian C Talbot; David B A Silk
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2008-05-07
Journal Detail:
Title:  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association     Volume:  6     ISSN:  1542-7714     ISO Abbreviation:  Clin. Gastroenterol. Hepatol.     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-06-13     Completed Date:  2008-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101160775     Medline TA:  Clin Gastroenterol Hepatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  707-9     Citation Subset:  IM    
Centre for Medical and Surgical Gastroenterology and Hepatology, Princess Grace Hospital, London, United Kingdom.
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Anti-Inflammatory Agents / therapeutic use
Child, Preschool
Colectomy / adverse effects*
Colitis, Ulcerative / surgery*
Inflammatory Bowel Diseases / drug therapy,  etiology*
Middle Aged
Time Factors
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Anti-Inflammatory Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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