| Idiopathic small-intestinal inflammation after colectomy for ulcerative colitis. | |
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MedLine Citation:
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PMID: 18467187 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND & AIMS: Severe ileostomy dysfunction with high ileostomy volumes or severe diarrhea after panproctocolectomy and restorative ileo-anal pouch formation are a rare but serious development after surgery for ulcerative colitis (UC). The incidence, severity, morbidity, and mortality are poorly documented in the literature. METHODS: We describe the case of a patient who developed life-threatening diarrhea after surgery for UC and review the literature. RESULTS: Eight cases have now been described in the literature. Small-bowel disease has developed up to 17 months after colectomy. Most cases responded to corticosteroid therapy. A single case in which this treatment was delayed was fatal. CONCLUSIONS: This is a rare sequel to colectomy for UC, but one which is serious and can be fatal. If the diagnosis is made promptly, a full response to treatment can be expected and the long-term outlook is excellent. |
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Authors:
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Ian R Gooding; Roger Springall; Ian C Talbot; David B A Silk |
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Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2008-05-07 |
Journal Detail:
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Title: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Volume: 6 ISSN: 1542-7714 ISO Abbreviation: Clin. Gastroenterol. Hepatol. Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-06-13 Completed Date: 2008-08-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101160775 Medline TA: Clin Gastroenterol Hepatol Country: United States |
Other Details:
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Languages: eng Pagination: 707-9 Citation Subset: IM |
Affiliation:
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Centre for Medical and Surgical Gastroenterology and Hepatology, Princess Grace Hospital, London, United Kingdom. ian_gooding@yahoo.co.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adrenal Cortex Hormones / therapeutic use Adult Anti-Inflammatory Agents / therapeutic use Child, Preschool Colectomy / adverse effects* Colitis, Ulcerative / surgery* Diarrhea Female Humans Inflammatory Bowel Diseases / drug therapy, etiology* Male Middle Aged Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Anti-Inflammatory Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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