| Idiopathic severe constriction of the fetal ductus arteriosus: a possible underestimated pathophysiology. | |
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MedLine Citation:
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PMID: 20845046 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Idiopathic intrauterine constriction/closure of the ductus arteriosus, which is distinct from that secondary to maternal exposure to non-steroidal anti-inflammatory drugs, such as indomethacin, or structural cardiac defect, is an uncommon event that often results in severe fetal-neonatal morbidity and mortality. We reported a case of idiopathic fetal ductal constriction, in which the diagnosis was confirmed by documentation of an abnormal four-chamber view of the fetal heart at 38 weeks of gestation on obstetric ultrasound examination. A female infant weighing 2,816 g was born by Cesarean section, and her postnatal course was mild; transient tachypnea requiring only several days of supplemental oxygen with spontaneous regression of the abnormal echocardiographic findings by 3 months of age. The incidence of idiopathic constriction/closure of the fetal ductus arteriosus may be underestimated, particularly with a negative history of maternal drug exposure and mild postnatal clinical presentation. |
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Authors:
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Yoshio Shima; Hiroko Ishikawa; Yoshikatsu Matsumura; Kentaro Yashiro; Mizue Nakajima; Makoto Migita |
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Publication Detail:
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Type: Journal Article Date: 2010-09-16 |
Journal Detail:
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Title: European journal of pediatrics Volume: 170 ISSN: 1432-1076 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: Germany |
Other Details:
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Languages: eng Pagination: 237-40 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Nippon Medical School, Tokyo, Japan, shima-p@nms.ac.jp. |
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