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Idiopathic retroperitoneal fibrosis with particular perirenal and intrarenal extension associated with left renal artery stenosis. The atheromatous periaortitis with retroperitoneal fibrosis suggests a pathogenic relationship between atherosclerosis and fibrosis?
MedLine Citation:
PMID:  21327674     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We present a case of idiopathic retroperitoneal fibrosis (RPF) in a female patient of 45 years, obese (BMI = 39 kg/sqm), hypertensive since 2005, with diabetes mellitus treated with diet and diabetes insipidus in whom, during a routine control, the following has been found: serum creatinine 1.74 mg/dl, and an inflammatory syndrome associated with fever. Spiral-CT (Multi-slice-Sensation 64) scan shows retroperitoneal fibrosis in relation with periaortitis that affects the thoracic and abdominal aorta. RPF is extending perirenally and at the level of the renal hilum with subsequent calyceal dilations (hydrocalycosis) associated with left renal artery stenosis. The particularity of the case is represented by the perirenal and intrarenal evolution of fibrosis with left renal artery stenosis with moderate impairment of renal function reversible under treatment with Tamoxifen. This case, with chronic periaortitis subsequent to an extended aortic atherosclerosis with retroperitoneal fibrosis can be representative for the pathogenic relationship between atherosclerosis and fibrosis.
Authors:
Gheorghe Gluhovschi; Gheorghe Bozdog; Gratian Miclaus; Tudor Puscasiu; Cristina Gluhovschi; Flaviu Bob; Silvia Velciov; Ligia Petrica; Virginia Trandafirescu; Florica Gadalean
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-17
Journal Detail:
Title:  Wiener klinische Wochenschrift     Volume:  -     ISSN:  1613-7671     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  21620870R     Medline TA:  Wien Klin Wochenschr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Nephrology, County Emergency Hospital, University of Medicine and Pharmacy, Timisoara, Romania, ggluhovschi@yahoo.com.
Vernacular Title:
Idiopathische retroperitoneale Fibrose mit peri- und intrarenaler Ausbreitung mit linker Nierenarterienstenose. Legt das gemeinsame Vorkommen einer atheromatösen Periaortitis mit einer retroperitonealen Fibrose einen Zusammenhang der Pathogenese von Atherosklerose und Fibrose nahe?
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