Document Detail

Idiopathic retroperitoneal fibrosis: the case for nonsurgical treatment.
MedLine Citation:
PMID:  16831158     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To review a 10-year experience of medical treatment for idiopathic retroperitoneal fibrosis (RPF), a rare condition of unknown causes, which may obstruct the ureter and for which treatment includes ureterolysis and relief of obstruction, and medical treatment with steroids with or without immunosuppressive medication. PATIENTS AND METHODS: Of 31 patients with RPF treated between 1996 and 2004, 28 had idiopathic disease. Ureteric stents were used to relieve the obstruction in all patients, 12 had previous nephrostomies, 16 were given steroids and only one was treated with ureterolysis. RESULTS: In all, 28 patients were followed for a mean of 51.17 months; the symptoms were relieved in all cases. Renal function, where impaired, improved dramatically in all patients. Fifteen patients (54%) are free of stents and medication after a mean (range) follow-up of 60.9 (24-110) months. CONCLUSION: Idiopathic RPF responds well to conservative management consisting of relief of urinary tract obstruction and steroids.
Cristian P Ilie; Richard J Pemberton; David A Tolley
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  BJU international     Volume:  98     ISSN:  1464-4096     ISO Abbreviation:  BJU Int.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-11     Completed Date:  2006-07-25     Revised Date:  2007-01-16    
Medline Journal Info:
Nlm Unique ID:  100886721     Medline TA:  BJU Int     Country:  England    
Other Details:
Languages:  eng     Pagination:  137-40     Citation Subset:  IM    
Department of Urology, Central Military Hospital, Bucharest, Romania.
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MeSH Terms
Aged, 80 and over
Follow-Up Studies
Middle Aged
Pain / etiology
Retroperitoneal Fibrosis / drug therapy*,  pathology
Retrospective Studies
Steroids / therapeutic use*
Ureteral Obstruction / drug therapy*,  pathology
Reg. No./Substance:
Comment In:
BJU Int. 2006 Nov;98(5):1123-4   [PMID:  17034618 ]

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