Document Detail

Idiopathic renal infarction.
MedLine Citation:
PMID:  16564787     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Renal infarction may be an underrecognized disorder. Classical teaching holds that cardioemboli, notably in the setting of arterial fibrillation, are responsible. The expanding use of contrast enhanced computed tomography (CT) in patients with acute abdomen may change the spectrum of renal infarction. METHODS: Twenty-seven consecutive patients presenting to a single university hospital with nontraumatic CT-documented acute renal infarction were studied and stratified according to the presence or absence of cardiac disease, either obvious at presentation or detected during work-up. RESULTS: Eleven patients (41%) had obvious cardiac disease, including atrial fibrillation in all but one. Sixteen patients (59%) had no discernible structural or arrhythmic cardiac disease and were classified as idiopathic group. Patients in the idiopathic group were significantly younger (median age in years [interquartile range]: 48 [41-53] versus 75 [53-82] years, P = .003) and, besides smoking, had fewer traditional cardiovascular risk factors. CONCLUSION: Acute renal infarction may occur in individuals of middle age without risk factors for cardioembolism. In patients with renal colic without lithiasis the diagnosis of renal infarction should be considered especially if serum lactate dehydrogenase is elevated, even in the absence of atrial fibrillation.
Rob Bolderman; Raymond Oyen; Anton Verrijcken; Daniël Knockaert; Steven Vanderschueren
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of medicine     Volume:  119     ISSN:  1555-7162     ISO Abbreviation:  Am. J. Med.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-03-27     Completed Date:  2006-04-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  356.e9-12     Citation Subset:  AIM; IM    
Department of General Internal Medicine, University Hospital, Leuven, Belgium.
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MeSH Terms
Acute Disease
Aged, 80 and over
C-Reactive Protein / metabolism
Diagnosis, Differential
Hematuria / etiology
Infarction / diagnosis*
Kidney / blood supply*,  radiography
Kidney Diseases / diagnosis*,  enzymology,  pathology,  radiography
L-Lactate Dehydrogenase / blood
Leukocyte Count
Middle Aged
Prospective Studies
Retrospective Studies
Risk Factors
Reg. No./Substance:
9007-41-4/C-Reactive Protein; EC Dehydrogenase

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