Document Detail

Idiopathic normal pressure hydrocephalus: results of a prospective cohort of 236 shunted patients.
MedLine Citation:
PMID:  22327703     Owner:  NLM     Status:  In-Process    
AIM: To describe the outcomes and complication rates in 236 patients with idiopathic normal pressure hydrocephalus (INPH) after treatment.
PATIENTS AND METHODS: Among a cohort of 257 patients with suspected INPH, 244 were shunted and 236 were followed up at 6 months after shunting (145 men [61.4%] and 91 women [38.6%] with a median age of 75 years). The study protocol of these patients included clinical, radiological, neuropsychological and functional assessment. The decision to shunt patients was based on continuous intracranial pressure monitoring and CSF dynamics studies. A differential low-pressure valve system, always combined with a gravity compensating device, was implanted in 99% of the patients.
RESULTS: After shunting, 89.9% of the patients showed clinical improvement (gait improved in 79.3% of patients, sphincter control in 82.4%, and dementia in 63.7%). Two patients (0.8%) died. Early postsurgical complications were found in 13 of the 244 shunted patients (5.3%). Six months after shunting, the follow-up CT showed asymptomatic hygromas in 8 of the 236 (3.4%). Additional postsurgical complications were found in 7 patients (3%), consisting of 6 subdural hematomas (3 acute and 3 chronic) and 1 distal catheter infection.
CONCLUSIONS: Currently, a high percentage of patients with INPH can improve after shunting, with early and late complication rates of less than 12%.
Maria Antonia Poca; Elisabeth Solana; Francisco Ramón Martínez-Ricarte; Mónica Romero; Dario Gándara; Juan Sahuquillo
Related Documents :
21953123 - Expanding the phenotype of late-onset pompe disease: tongue weakness: a new clinical ob...
22414233 - Postdialysis blood pressure rise predicts long-term outcomes in chronic hemodialysis pa...
773413 - The treatment of vitiligo with topical corticosteroids. light and electronmicroscopic s...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta neurochirurgica. Supplement     Volume:  114     ISSN:  0065-1419     ISO Abbreviation:  Acta Neurochir. Suppl.     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100962752     Medline TA:  Acta Neurochir Suppl     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  247-53     Citation Subset:  IM    
Department of Neurosurgery, Universitat Autònoma de Barcelona, Barcelona, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  On the method of a randomised comparison of programmable valves with and without gravitational units...
Next Document:  Idiopathic normal pressure hydrocephalus (iNPH) and co-morbidity: an outcome analysis of 134 patient...