Document Detail

Idiopathic isolated orbicularis weakness.
MedLine Citation:
PMID:  22322997     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Orbicularis weakness is commonly associated with seventh nerve palsy or neuromuscular and myopathic conditions such as myotonic dystrophy and myasethenia gravis. We report four cases of idiopathic isolated orbicularis weakness.
METHODS: All four cases were female and the presenting symptoms of ocular irritation and epiphora had been present for over 7 years in three patients. All patients had lagophthalmos and three had ectropion. Three patients underwent full investigations which excluded known causes of orbicularis weakness. Two patients underwent oribularis oculi muscle biopsy and histological confirmation of orbicularis atrophy.
RESULTS: All patients underwent surgery to specifically address the orbicularis weakness with satisfactory outcomes and alleviation of symptoms in all cases. Isolated orbicularis weakness may be a relatively common entity that is frequently overlooked.
CONCLUSION: Early recognition of this condition may lead to better management and prevent patients undergoing unnecessary surgical procedures.
O P MacVie; M A Majid; H M Husssin; T Ung; R M Manners; I Ormerod; J Pawade; R A Harrad
Related Documents :
17704117 - Therapeutic drug monitoring of the hiv protease inhibitor atazanavir in clinical practice.
10407777 - D-2-hydroxyglutaric aciduria: further clinical delineation.
535887 - Interstitial deletion 13q syndromes: a report on two unrelated patients.
8960317 - Myopathology in patients with a noonan phenotype.
984787 - Pharmacokinetics of cefamandole in patients undergoing hemodialysis and peritoneal dial...
9869167 - 4g/5g polymorphism of pai-1 gene promoter and fibrinolytic capacity in patients with de...
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2012-02-10
Journal Detail:
Title:  Eye (London, England)     Volume:  26     ISSN:  1476-5454     ISO Abbreviation:  Eye (Lond)     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-05-10     Completed Date:  2012-07-18     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  8703986     Medline TA:  Eye (Lond)     Country:  England    
Other Details:
Languages:  eng     Pagination:  746-8     Citation Subset:  IM    
Department of Ophthalmology, Bristol Eye Hospital, Bristol, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Eyelid Diseases / diagnosis*,  surgery
Muscle Weakness / diagnosis*,  surgery
Oculomotor Muscles / pathology*
Ophthalmologic Surgical Procedures

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Large variations in the magnetic ordering behavior of EuCu(2)As(2) with the application of external ...
Next Document:  Microperimetric changes in neovascular age-related macular degeneration treated with ranibizumab.