Document Detail

Idiopathic infantile arterial calcification: prenatal diagnosis and postnatal presentation.
MedLine Citation:
PMID:  20420290     Owner:  NLM     Status:  MEDLINE    
Idiopathic infantile arterial calcification (IIAC) is a rare disease of unknown etiology, which is characterized by arterial calcification. A 29-year-old primigravida at 33 weeks' gestation was referred for further evaluation for polyhydramniosis. An ultrasonographic examination revealed an intrauterine growth restricted fetus, pericardial effusion, increased renal cortical echogenicity with sparing of corticomedullary differentiation, and diffuse arterial calcifications involving the aorta, pulmonary artery, common iliac arteries, renal arteries, and common carotid arteries. At 35 weeks of gestation a cesarean section was performed because of fetal distress. A 1900 g male infant was delivered. Postnatal examination confirmed the diagnosis of IIAC with dysmorphic features (clinodactily and low-set ears) and normal constitutional karyotype. The baby died when he was four months old in the newborn care unit. During routine obstetric ultrasonography, the combination of polyhydramniosis and intrauterine growth restriction may necessitate examination of the major vessels for presumptive a diagnosis of IIAC.
A Cansu; A Ahmetoglu; M Mutlu; S Guven; M A Osmanagaoglu
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical and experimental obstetrics & gynecology     Volume:  37     ISSN:  0390-6663     ISO Abbreviation:  Clin Exp Obstet Gynecol     Publication Date:  2010  
Date Detail:
Created Date:  2010-04-27     Completed Date:  2010-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802110     Medline TA:  Clin Exp Obstet Gynecol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  73-5     Citation Subset:  IM    
Department of Radiology, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey.
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MeSH Terms
Arteries / pathology*
Calcinosis / pathology*
Fatal Outcome
Fetal Growth Retardation / diagnosis
Heart Septal Defects, Atrial / ultrasonography
Hypertension, Pulmonary / ultrasonography
Polyhydramnios / diagnosis
Prenatal Diagnosis*
Tomography, X-Ray Computed
Tricuspid Valve Insufficiency / ultrasonography
Vascular Diseases / pathology*

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