Document Detail


Idiopathic infantile arterial calcification in siblings: radiologic diagnosis and successful treatment.
MedLine Citation:
PMID:  416189     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Idiopathic infantile arterial calcification is a disorder of unknown etiology manifested by widespread arterial calcification. This usually leads to early death from coronary artery occlusion. In 12 of the 75 cases in the literature, radiographs were taken and it was possible to make the diagnosis in them all. We present two patients, siblings, in whom the diagnosis was established radiologically. The nature of the calcium deposits was studied in one of the infants and proved to be calcium hydroxyapatite. Therapy with diphosphonate was apparently successful in the other child.
Authors:
M Meradji; V H de Villeneuve; J Huber; W C de Bruijn; R G Pearse
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  92     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1978 Mar 
Date Detail:
Created Date:  1978-05-17     Completed Date:  1978-05-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  401-5     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Arteriosclerosis / drug therapy,  genetics*,  radiography
Calcinosis / drug therapy,  genetics*,  radiography
Coronary Disease / genetics
Etidronic Acid / therapeutic use
Female
Humans
Infant, Newborn
Infant, Newborn, Diseases / genetics*
Male
Pregnancy
Chemical
Reg. No./Substance:
2809-21-4/Etidronic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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