Document Detail

Idiopathic hypertrophic subaortic stenosis in pregnancy.
MedLine Citation:
PMID:  1169900     Owner:  NLM     Status:  MEDLINE    
The coexistence of pregnancy and idiopathic hypertrophic subaortic stenosis is a potentially dangerous combination. We report a 23-year-old white woman with idiopathic hypertrophic subaortic stenosis and pregnancy who presented with severe symptoms (Class IV) and modest outflow obstruction associated with marked mitral regurgitation. After delivery, the evidence for significant mitral regurgitation regressed, while the outflow obstruction seemed unchanged. However, she returned to Functional Class II. We review the mechanisms by which pregnancy and labor may alter the hemodynamics of idiopathic hypertrophic subaortic stenosis and we discuss recommendations for the management of these patients during pregnancy, labor, and the immediate postpartum period. We conclude that despite increasing symptoms, most women with diopathic hypertrophic subaortic stenosis can tolerate pregnancy and a vaginal delivery.
A J Kolibash; D E Ruiz; R P Lewis
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Annals of internal medicine     Volume:  82     ISSN:  0003-4819     ISO Abbreviation:  Ann. Intern. Med.     Publication Date:  1975 Jun 
Date Detail:
Created Date:  1975-09-09     Completed Date:  1975-09-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372351     Medline TA:  Ann Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  791-4     Citation Subset:  AIM; IM    
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MeSH Terms
Aortic Stenosis, Subvalvular* / diagnosis,  drug therapy
Cardiomyopathy, Hypertrophic*
Delivery, Obstetric
Heart Catheterization
Heart Murmurs
Heart Rate
Pregnancy Complications, Cardiovascular* / diagnosis,  drug therapy
Propranolol / therapeutic use
Pulmonary Edema / etiology
Reg. No./Substance:

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