Document Detail


Idiopathic granulomatous pneumonia in seven horses.
MedLine Citation:
PMID:  14667086     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The history, clinical signs and pathological findings in seven adult horses with histologically confirmed idiopathic granulomatous disease, primarily of the lungs, are reviewed. They ranged in age from eight to 21 years, five were geldings and two were females, they belonged to five breeds and there were no seasonal or geographical associations. The primary clinical signs were chronic weight loss, exercise intolerance and respiratory distress which did not respond to conventional treatment. The most consistent physical findings were depression, anorexia, tachycardia, tachypnoea and adventitious lung sounds. Thoracic radiographs revealed a diffuse, structured, nodular, interstitial pulmonary pattern in each horse. Haematological measurements suggested a chronic inflammatory process and the cytology of transtracheal washes was consistent with a mild suppurative inflammation. Idiopathic granulomatous pneumonia was confirmed histologically in each of the horses, either postmortem or by a lung biopsy. The horses responded poorly to medical treatment and only one of three treated horses is still alive.
Authors:
N Pusterla; P A Pesavento; P Smith; M M Durando; K G Magdesian; W D Wilson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Veterinary record     Volume:  153     ISSN:  0042-4900     ISO Abbreviation:  Vet. Rec.     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-12-11     Completed Date:  2004-03-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  England    
Other Details:
Languages:  eng     Pagination:  653-5     Citation Subset:  IM    
Affiliation:
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Female
Granuloma / drug therapy,  pathology,  radiography,  veterinary*
Horse Diseases / drug therapy,  pathology*,  radiography
Horses
Lung / pathology*
Male
Pneumonia / drug therapy,  pathology,  radiography,  veterinary*
Prognosis
Radiography, Thoracic / veterinary
Retrospective Studies
Treatment Outcome
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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