Document Detail

Idiopathic esophageal ulceration in the acquired immunodeficiency syndrome: radiologic reappraisal in 10 patients.
MedLine Citation:
PMID:  8161896     Owner:  NLM     Status:  MEDLINE    
Idiopathic esophageal ulceration in patients with AIDS has previously been described. Establishing this diagnosis is important because of the excellent response of these ulcers to corticosteroid therapy. We studied 10 such patients with esophagography and endoscopy. HIV was isolated from the ulcer base in six of the 10 patients utilizing various techniques including in situ hybridization. No other organisms were found. All of the ulcers were in the distal half of the esophagus and were solitary in eight of the 10 patients. The solitary ulcers were large (2.5 x 2.0 cm to 12 x 9 cm) and deep (> 0.5 cm) with undermined margins. In three patients, fistulae arose from the distal esophagus and crossed the gastroesophageal junction. In one patient, a huge idiopathic ulcer perforated into the mediastinum. These latter findings are not seen in the more common ulcerating AIDS esophagitides due to herpes simplex and cytomegalovirus.
D Frager; D P Kotler; J Baer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Abdominal imaging     Volume:  19     ISSN:  0942-8925     ISO Abbreviation:  Abdom Imaging     Publication Date:    1994 Jan-Feb
Date Detail:
Created Date:  1994-05-24     Completed Date:  1994-05-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9303672     Medline TA:  Abdom Imaging     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2-5     Citation Subset:  IM; X    
Department of Radiology, Columbia University College of Physicians and Surgeons, St. Luke's/Roosevelt Hospital Center, New York, NY 10025.
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MeSH Terms
Acquired Immunodeficiency Syndrome / complications*
Esophageal Diseases / complications,  pathology,  radiography*
Esophagus / pathology,  radiography
Middle Aged
Ulcer / complications,  radiography

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