| Idiopathic bronchiolitis mimicking diffuse panbronchiolitis. | |
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MedLine Citation:
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PMID: 12737282 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Diffuse panbronchiolitis (DPB) is a distinct sinobronchial syndrome which has been almost exclusively reported in East Asia; only a few cases have been observed in non-Asians so far. Since 1990, when one of us described the first European case, we have screened all patients presenting with a clinical, physiopathological and radiological pattern compatible with DPB, in order to assess if the paucity of proven cases in Europe could reflect a lack of awareness of this disease among both pulmonologists and pathologists. Over a 10-years period we identified four additional DPBs, but also interestingly observed five cases of "idiopathic" bronchiolitis (IB) that had both clinical symptoms and high-resolution computed tomography (HRCT) findings indistinguishable from those of DPB, but did not show the typical histological changes. All these patients were Caucasians and presented with dyspnea, productive cough, an obstructive or mixed impairment on pulmonary function tests and chest HRCT features strongly suggesting a grade II to IV DPB. We suggest that diseases classified as IB in this study might be homogeneous entities which are clinically and radiologically similar to DPB. |
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Authors:
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Venerino Poletti; Marco Chilosi; Rocco Trisolini; Alessandra Cancellieri; Maurizio Zompatori; Luigi Lazzari Agli; Maurizio Boaron; W Schulte; D Theegarten; J Guzman; Ulrich Costabel |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders Volume: 20 ISSN: 1124-0490 ISO Abbreviation: Sarcoidosis Vasc Diffuse Lung Dis Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-05-09 Completed Date: 2004-01-09 Revised Date: 2009-12-10 |
Medline Journal Info:
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Nlm Unique ID: 9610928 Medline TA: Sarcoidosis Vasc Diffuse Lung Dis Country: Italy |
Other Details:
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Languages: eng Pagination: 62-8 Citation Subset: IM |
Affiliation:
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Dipartimento di Malattie dell'Apparato Respiratorio e del Torace, Ospedale G.B. Morgagni, Forlì, Italy. vepolet@tin.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Anti-Bacterial Agents / therapeutic use* Bronchiolitis / classification, diagnosis*, drug therapy, pathology Bronchoalveolar Lavage Fluid Bronchoscopy Chronic Disease Diagnosis, Differential Erythromycin / therapeutic use* Female Humans Male Middle Aged Respiratory Function Tests Retrospective Studies Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 114-07-8/Erythromycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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