Document Detail


Idiopathic acquired panmyelopathy in pregnancy. A case report.
MedLine Citation:
PMID:  685721     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case of idopathic acquired panmyelopathy (aplastic anaemia) in pregnancy in a 32-year-old woman is presented. The outcome for mother and child was favourable. Special attention is paid to the management of the delivery. Another aspect of interest is the haematologic status of the child. In panmyelopathy an immunologic mechanism may operate as indicated by the finding of platelet membrane associated immunoglobulins, which were also present in our patient. If the bone marrow lesions in this disease are indeed due to immunological injury, they are mediated by immune complexes or by a cellular mechanism, for it is well know that IgG antibodies may pass through the placenta and induce lysis of circulating blood cells in the newborn. There was no evidence of bone marrow damage in the infant. This is in accordance with the cases mentioned in the literature.
Authors:
J P Samson; T M Brouwers; H J Huisjes; G S van der Schans; H O Nieweg
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta medica Scandinavica     Volume:  204     ISSN:  0001-6101     ISO Abbreviation:  Acta Med Scand     Publication Date:  1978  
Date Detail:
Created Date:  1978-10-25     Completed Date:  1978-10-25     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0370330     Medline TA:  Acta Med Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  131-5     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Anemia, Aplastic* / immunology
Blood Platelets / immunology
Blood Transfusion
Bone Marrow / immunology
Cell Membrane / immunology
Cesarean Section
Female
Humans
Immunoglobulin G
Infant, Newborn
Pregnancy
Pregnancy Complications, Hematologic* / immunology
Receptors, Antigen, B-Cell
Chemical
Reg. No./Substance:
0/Immunoglobulin G; 0/Receptors, Antigen, B-Cell

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