Document Detail

Identifying unrecognized airflow obstruction in cases with lifestyle-related diseases using a data mining system with electronic medical records.
MedLine Citation:
PMID:  21473425     Owner:  NLM     Status:  In-Process    
BACKGROUND: Airflow obstruction is the most important pathophysiologic factor in chronic obstructive pulmonary disease (COPD). Although the prevalence of airflow obstruction has been increasing worldwide, airflow obstruction is often under-recognized in clinical practice because of insufficient use of spirometry. The aim of the present study was to identify unrecognized airflow obstruction in cases with lifestyle-related diseases using a data mining system that we have developed for use with electronic medical records.
METHODS: Clinical, spirometric data on 27,111 patients aged 40 years or older treated during the period from January 1999 to December 2008 was retrospectively collected from the electronic medical records of the Nihon University School of Medicine clinical data warehouse. Airflow obstruction was defined according to the criteria established by the Global Initiative for Chronic Obstructive Lung Disease (GOLD).
RESULTS: Of the 27,111 patients, 6,098 (22.5%) showed airflow obstruction. Airflow obstruction was significantly more frequent in males, the elderly and smokers. The prevalence of airflow obstruction in patients with atherosclerosis (29.3%) was greater than that in patients with dyslipidemia (24.3%), diabetes mellitus (23.1%) or hypertension (27.1%). Only 14% of patients with airflow obstruction had a previous diagnosis of COPD.
CONCLUSIONS: Latent COPD patients with airflow obstruction are highly prevalent, not only in those over 70 years of age with lifestyle-related diseases, but also in middle-aged patients. Spirometry should be widely used for patients with lifestyle-related diseases and a history of smoking, to effectively detect undiagnosed COPD.
Ken Matsumoto; Yasuo Takahashi; Yasuhiro Gon; Toshiki Akahoshi; Tomohiro Nakayama; Satoshi Asai; Shu Hashimoto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Rinsho byori. The Japanese journal of clinical pathology     Volume:  59     ISSN:  0047-1860     ISO Abbreviation:  Rinsho Byori     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-04-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984781R     Medline TA:  Rinsho Byori     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  128-33     Citation Subset:  IM    
Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Itabashi-ku, Tokyo 173-8610, Japan.
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