Document Detail

Identifying the causes of stillbirth: a comparison of four classification systems.
MedLine Citation:
PMID:  18771999     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To identify the classification protocol for stillbirth that minimizes the rate of unexplained causes. STUDY DESIGN: All stillbirths at > 22 weeks from 1995-2007 underwent a workup inclusive of fetal ultrasonography, amniocentesis for karyotype and cultures, placental histology, fetal autopsy, skin biopsy, total body X-ray, maternal testing for thrombophilias, TORCH, Parvovirus spp, thyroid function, indirect Coombs, Kleiheuer-Betke test, and genital cultures. To such a cohort, we applied the 4 most commonly used classification protocols. RESULTS: The stillbirth rate during the study period was 0.4% (154/37,958). The RoDeCo classification provided the lowest rate of unexplained stillbirth (14.3%) compared with Wigglesworth (47.4%), de Galan-Roosen (18.2%), and Tulip (16.2%) classifications. Mean gestational age at stillbirth in unexplained vs explained stillbirth was similar in the 4 protocols. CONCLUSION: Adoption of a consistent and appropriate workup protocol can reduce the rate of unexplained stillbirth to 14%.
Patrizia Vergani; Sabrina Cozzolino; Elisa Pozzi; Maria Serena Cuttin; Massimiliano Greco; Sara Ornaghi; Valeria Lucchini
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  199     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-05     Completed Date:  2008-10-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  319.e1-4     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, University of Milano-Bicocca, Monza, Italy.
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MeSH Terms
Cause of Death*
Classification / methods
Fetal Growth Retardation / epidemiology
Fetus / abnormalities
Gestational Age
Placenta Diseases / epidemiology
Retrospective Studies
Risk Factors
Stillbirth / epidemiology*

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