| Identifying the causes of stillbirth: a comparison of four classification systems. | |
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MedLine Citation:
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PMID: 18771999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To identify the classification protocol for stillbirth that minimizes the rate of unexplained causes. STUDY DESIGN: All stillbirths at > 22 weeks from 1995-2007 underwent a workup inclusive of fetal ultrasonography, amniocentesis for karyotype and cultures, placental histology, fetal autopsy, skin biopsy, total body X-ray, maternal testing for thrombophilias, TORCH, Parvovirus spp, thyroid function, indirect Coombs, Kleiheuer-Betke test, and genital cultures. To such a cohort, we applied the 4 most commonly used classification protocols. RESULTS: The stillbirth rate during the study period was 0.4% (154/37,958). The RoDeCo classification provided the lowest rate of unexplained stillbirth (14.3%) compared with Wigglesworth (47.4%), de Galan-Roosen (18.2%), and Tulip (16.2%) classifications. Mean gestational age at stillbirth in unexplained vs explained stillbirth was similar in the 4 protocols. CONCLUSION: Adoption of a consistent and appropriate workup protocol can reduce the rate of unexplained stillbirth to 14%. |
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Authors:
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Patrizia Vergani; Sabrina Cozzolino; Elisa Pozzi; Maria Serena Cuttin; Massimiliano Greco; Sara Ornaghi; Valeria Lucchini |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 199 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-09-05 Completed Date: 2008-10-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 319.e1-4 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of Milano-Bicocca, Monza, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cause of Death* Classification / methods Female Fetal Growth Retardation / epidemiology Fetus / abnormalities Gestational Age Humans Placenta Diseases / epidemiology Pregnancy Retrospective Studies Risk Factors Stillbirth / epidemiology* |
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