| Identification of viruses with bi- and trisegmented double-stranded RNA genome in faeces of children with gastroenteritis. | |
| | |
MedLine Citation:
|
PMID: 8356343 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Polyacrylamide gel electrophoresis of nucleic acid extracted from faecal samples of diarrhoeic children revealed the presence of group A rotavirus in 50 (23.4%) samples and group C rotavirus in 1 (0.5%) sample out of 214 tested. One other sample showed the presence of three bands (with apparent length of 2.92, 2.37 and 1.32 kbp) which by enzymatic digestion analysis, were shown to consist of double-stranded RNA (dsRNA). The sample was shown by electron microscopy to contain virus particles with a diameter of 32-34 nm. On the basis of morphology and genomic characteristics, this virus closely resembles a virus hitherto described only in chickens by Leite et al. in 1990 and tentatively named "picotrirnavirus". From the same group of 214, one sample containing a "picobirnavirus" was also identified. Thus, small icosahedral viruses with either a bior trisegmented dsRNA genome appear to infect humans. However, their pathogenic potential remains to be established. |
| | |
Authors:
|
J E Ludert; F Liprandi |
Related Documents
:
|
22814713 - Lymphomatoid granulomatosis and other epstein-barr virus associated lymphoproliferative... 10213893 - Parvovirus b19 infection in pregnancy. 19871563 - Inhibition of phosphorylation of glucose in mouse brains by viruses and its prevention ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Research in virology Volume: 144 ISSN: 0923-2516 ISO Abbreviation: Res. Virol. Publication Date: 1993 May-Jun |
Date Detail:
|
Created Date: 1993-09-21 Completed Date: 1993-09-21 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8907469 Medline TA: Res Virol Country: FRANCE |
Other Details:
|
Languages: eng Pagination: 219-24 Citation Subset: IM |
Affiliation:
|
Laboratorio de Biología de Virus, Instituto Venezolano de Investig aciones Científicas (IVIC), Caracas. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Child Electrophoresis, Polyacrylamide Gel Feces / microbiology Gastroenteritis / microbiology* Humans Microscopy, Electron RNA Viruses / genetics, isolation & purification*, ultrastructure RNA, Double-Stranded / genetics, isolation & purification* RNA, Viral / genetics, isolation & purification* |
| Chemical | |
Reg. No./Substance:
|
0/RNA, Double-Stranded; 0/RNA, Viral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cardiovascular and catecholamine responses to acute haemorrhage in anaesthetized potassium-adapted r...
Next Document: Coronary artery lesions and human immunodeficiency virus infection.