| Identification of two cell cycle regulated genes affecting the beta 1,3-glucan content of cell walls in Saccharomyces cerevisiae. | |
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MedLine Citation:
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PMID: 7828729 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The Calcofluor white-hypersensitive mutants cwh52 and cwh53 are severely reduced in beta 1,3-glucan. CWH52 was equivalent to GAS1. CWH53 represented a new gene, located on the right arm of chromosome XII, and predicted to encode a 215 kDa protein with multiple transmembrane domains. The transcription of CWH53 was cell cycle-dependent and, similar to GAS1/CWH52, increased in late G1, indicating that the formation of beta-glucan is cell cycle-regulated. Further, in some mutant alleles of both gas1/cwh52 and cwh53 lethal concentrations of Calcofluor induced growth arrest at a specific phase of the cell cycle. |
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Authors:
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A F Ram; S S Brekelmans; L J Oehlen; F M Klis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: FEBS letters Volume: 358 ISSN: 0014-5793 ISO Abbreviation: FEBS Lett. Publication Date: 1995 Jan |
Date Detail:
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Created Date: 1995-02-23 Completed Date: 1995-02-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0155157 Medline TA: FEBS Lett Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 165-70 Citation Subset: IM |
Affiliation:
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Institute for Molecular Cell Biology, University of Amsterdam, The Netherlands. |
| Data Bank Information | |
Bank Name/Acc. No.:
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GENBANK/X80817 |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acid Sequence Base Sequence Cell Cycle / genetics* Cell Wall / metabolism* Chromosomes, Fungal Cloning, Molecular Consensus Sequence Gene Expression Regulation, Fungal* Glucans / metabolism* Molecular Sequence Data Mutation Oligodeoxyribonucleotides Saccharomyces cerevisiae / genetics*, growth & development, metabolism beta-Glucans* |
| Chemical | |
Reg. No./Substance:
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0/Glucans; 0/Oligodeoxyribonucleotides; 0/beta-Glucans; 9051-97-2/beta-1,3-glucan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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