| Identification of selected antihypertensive drugs by thin-layer chromatography. | |
| | |
MedLine Citation:
|
PMID: 893589 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A thin-layer chromatographic procedure is described for the qualitative identification of several antihypertensive drugs including certain thiazide diuretics spironolactone, triamterene, methyldopa and their metabolites. Utilization of new solvent developing systems and spray detecting reagents provides a method useful for the identification of these compounds in biologic fluids at low therapeutic concentrations. Sensitivity limits for these antihypertensive drugs are given, and alternate techniques to provide confirmatory analyses are also presented. |
| | |
Authors:
|
J E Wallace; H E Hamilton; H Skrdlant; L L Burkett; H Schwertner |
Related Documents
:
|
6280899 - Guanfacine and other centrally acting drugs in antihypertensive therapy; pharmacologica... 22833579 - Drugs of abuse and increased risk of psychosis development. 22838069 - Organic cation transporters in the blood-air barrier: expression and implications for p... 2048369 - The effects of antihypertensive agents on the quality of life in indian hypertensives. 22593459 - Serum pharmacokinetics in patients treated with transarterial chemoembolization (tace) ... 16046899 - New insights in the pharmacological therapy of arterial hypertension. 20795449 - Drug prescription habits in public and private health facilities in 2 provinces in sout... 17060519 - In vitro-clinical correlations for amphotericin b susceptibility in aids-associated cry... 15906029 - Successful management of cryoglobulinemia-induced leukocytoclastic vasculitis with thal... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
|
Title: Journal of chromatography Volume: 138 ISSN: 0021-9673 ISO Abbreviation: J. Chromatogr. Publication Date: 1977 Aug |
Date Detail:
|
Created Date: 1977-10-28 Completed Date: 1977-10-28 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0427043 Medline TA: J Chromatogr Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 111-8 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Antihypertensive Agents
/
urine* Chromatography, Thin Layer / methods Diuretics Humans Hydrochlorothiazide / urine Methyldopa / urine Reserpine / urine Sodium Chloride Symporter Inhibitors / urine Spironolactone / urine Triamterene / urine |
| Chemical | |
Reg. No./Substance:
|
0/Antihypertensive Agents; 0/Diuretics; 0/Sodium Chloride Symporter Inhibitors; 396-01-0/Triamterene; 50-55-5/Reserpine; 52-01-7/Spironolactone; 555-30-6/Methyldopa; 58-93-5/Hydrochlorothiazide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The quantitative determination of metabolites of 6-mercaptopurine in biological materials. II. Advan...
Next Document: Determination of thiocyanate in tissues and body fluids of animals by gas chromatography with electr...