| Identification of region specific genes by chromosome microdissection. | |
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MedLine Citation:
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PMID: 9062577 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chromosome microdissection is an extremely useful molecular cytogenetic tool for the characterization of chromosomal abnormalities in tumor cells. Although it has been used primarily in conjunction with fluorescence in situ hybridization (FISH), microdissection has also been useful for molecular analysis via microclone library construction. Recently, microdissection has been applied to the isolation of region specific cDNAs with sufficient success that gene discovery can now be added to the list of applications of this versatile molecular cytogenetic technique. |
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Authors:
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P S Meltzer; X Y Guan; Y A Su; E Gracia; J M Trent |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cancer genetics and cytogenetics Volume: 93 ISSN: 0165-4608 ISO Abbreviation: Cancer Genet. Cytogenet. Publication Date: 1997 Jan |
Date Detail:
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Created Date: 1997-03-26 Completed Date: 1997-03-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7909240 Medline TA: Cancer Genet Cytogenet Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 29-32 Citation Subset: IM |
Affiliation:
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Laboratory of Cancer Genetics, National Center for Human Genome Research, National Institutes of Health, Bethesda, Maryland 20892-4470, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chromosome Mapping
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methods* DNA, Complementary / isolation & purification Gene Amplification Humans In Situ Hybridization, Fluorescence / methods* Polymerase Chain Reaction / methods |
| Chemical | |
Reg. No./Substance:
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0/DNA, Complementary |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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