| Identification and quantitation of arachidonic-acid metabolic products in rabbit, rat and human saliva. | |
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MedLine Citation:
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PMID: 6318707 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Arachidonic-acid metabolites were identified in salivary secretions of rabbits, rats and man and in homogenates of rabbit parotid and submandibular glands. The following levels were determined in mixed saliva of healthy volunteers: PGE2, 0.65 +/- 0.8 ng/ml; PGF2 alpha, 0.41 +/- 0.06 ng/ml; serologically active hydroxyeicosatetraenoic acids (HETE) 319.6 +/- 36.6 ng/ml; serologically active 6-sulphidopeptide-containing leukotrienes 1.72 +/- 0.21 ng/ml (all values mean +/- SEM). In all instances, HETE markedly predominated over all other arachidonic-acid metabolites. |
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Authors:
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B Rigas; R A Lewis; K F Austen; E J Corey; L Levine |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Archives of oral biology Volume: 28 ISSN: 0003-9969 ISO Abbreviation: Arch. Oral Biol. Publication Date: 1983 |
Date Detail:
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Created Date: 1984-02-14 Completed Date: 1984-02-14 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0116711 Medline TA: Arch Oral Biol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1031-5 Citation Subset: D; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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12-Hydroxy-5,8,10,14-eicosatetraenoic Acid Animals Arachidonic Acid Arachidonic Acids / analysis, metabolism* Chromatography, High Pressure Liquid Dinoprost Dinoprostone Endocrine Glands / analysis Exocrine Glands / analysis Female Humans Leukotriene B4 / analysis Male Prostaglandins E / analysis Prostaglandins F / analysis Rabbits Radioimmunoassay Rats Rats, Inbred Strains Saliva / analysis* |
| Grant Support | |
ID/Acronym/Agency:
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AI-10356/AI/NIAID NIH HHS; CA-17309/CA/NCI NIH HHS; GM-27256/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Arachidonic Acids; 0/Prostaglandins E; 0/Prostaglandins F; 363-24-6/Dinoprostone; 506-32-1/Arachidonic Acid; 551-11-1/Dinoprost; 59985-28-3/12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 71160-24-2/Leukotriene B4 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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