| Identification of patients at high risk for recurrence of sustained ventricular tachycardia after healing of acute myocardial infarction. | |
| | |
MedLine Citation:
|
PMID: 1736607 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A prognostic index for nonfatal recurrences of ventricular tachycardia (VT) was developed using a retrospective analysis of a group of 206 patients with sustained monomorphic VT or ventricular fibrillation (VF) after healing of acute myocardial infarction. 74 patients (36%) (64 with VT and 10 with VF) had recurrences of sustained monomorphic VT during 3.4 +/- 9 years of follow-up. Three clinical variables were selected and weighted by stepwise logistic discriminant analysis of the study group. They were coded as follows: interval of myocardial infarction to arrhythmia (less than 2 months = 1; 2 to 6 months = 2; greater than 6 months = 3), drug therapy with or without sotalol (with = 1, without = 2), and VT or VF as the presenting arrhythmia (VT = 1, VF = 2). The prognostic index was: 3.41 - (0.56 x interval) - (1.94 x therapy) + (0.86 x arrhythmia). This index was validated prospectively in a test group of 158 consecutive patients with VT or VF after healing of acute myocardial infarction. Patients were allocated into different classes with decreasing prognostic index values associated with increasing risk for recurrences of VT. In the test group, 27 of 158 (17%) patients (22 with VT and 5 with VF) had recurrences of VT (follow-up of 2 +/- 2 years). Two risk classes of patients were identified: high risk for recurrences of VT (61%) corresponding to patients with a negative index; and low risk (4%) consisting of those with a positive index. Thus, using O as the cutoff point, the sensitivity, specificity, and positive and negative predictive values were 81, 89, 62 and 96%, respectively.(ABSTRACT TRUNCATED AT 250 WORDS) |
| | |
Authors:
|
L M Rodriguez; R Oyarzun; J Smeets; J Brachmann; C Schmitt; P Brugada; P Geelen; G Lipcsei; A Albert; H J Wellens |
Related Documents
:
|
21416547 - Functional outcomes related to the prevention of radiation-induced xerostomia: oral pil... 6853747 - Mexiletine in the treatment of recurrent ventricular tachycardia. prediction of long-te... 1695357 - A study of the use of flecainide acetate in the long-term management of cardiac arrhyth... 3137797 - Treatment of life-threatening ventricular tachycardia with encainide hydrochloride in p... 19335077 - Hand and ultrasonic instrumentation in combination with root-coverage surgery: a compar... 17163257 - Comparison of the efficacy and safety of 0.1% tacrolimus ointment with topical corticos... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The American journal of cardiology Volume: 69 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1992 Feb |
Date Detail:
|
Created Date: 1992-03-12 Completed Date: 1992-03-12 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 462-4 Citation Subset: AIM; IM |
Affiliation:
|
Department of Cardiology, University of Limburg, Academic Hospital, Maastricht, The Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Female Humans Male Middle Aged Myocardial Infarction / complications* Predictive Value of Tests Prognosis Recurrence Retrospective Studies Risk Factors Sensitivity and Specificity Tachycardia / etiology* Time Factors Ventricular Fibrillation / etiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Platelet function after in vivo and in vitro treatment with thrombolytic agents.
Next Document: Correlation of the complete version of the Selvester QRS scoring system with quantitative anatomic f...