| Identification of a novel e8/a4 BCR/ABL fusion transcript in a case of a transformed Sézary syndrome. | |
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MedLine Citation:
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PMID: 17768128 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This report deals with a case of Sézary syndrome, a rare peripheral T-cell lymphoproliferative disorder, in which cytogenetic analysis performed during the disease transformation revealed the presence of a t(9;22) (q34;q11.2) translocation. Molecular analyses identified a new transcript, an e8a4 BCR-ABL fusion mRNA which could be responsible for the disease transformation. |
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Authors:
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Evelyne Callet-Bauchu; Gilles Salles; Sophie Gazzo; Stéphane Dalle; Françoise Berger; Sandrine Hayette |
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Publication Detail:
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Type: Case Reports; Letter; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Haematologica Volume: 92 ISSN: 1592-8721 ISO Abbreviation: Haematologica Publication Date: 2007 Sep |
Date Detail:
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Created Date: 2007-09-04 Completed Date: 2008-01-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0417435 Medline TA: Haematologica Country: Italy |
Other Details:
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Languages: eng Pagination: 1277-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Chromosomes, Human, Pair 22 / genetics Chromosomes, Human, Pair 9 / genetics Fatal Outcome Female Fusion Proteins, bcr-abl / genetics* Humans In Situ Hybridization, Fluorescence Karyotyping Sezary Syndrome / diagnosis, drug therapy, genetics* Translocation, Genetic |
| Chemical | |
Reg. No./Substance:
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0/Fusion Proteins, bcr-abl |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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