Document Detail


Identification of a novel alkaliphilic esterase active at low temperatures by screening a metagenomic library from antarctic desert soil.
MedLine Citation:
PMID:  19411411     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A novel esterase was identified through functional screening of a metagenomic library in Escherichia coli obtained from Antarctic desert soil. The 297-amino-acid sequence had only low (<29%) similarity to a putative esterase from Burkholderia xenovorans. The enzyme was active over a temperature range of 7 to 54 degrees C and at alkaline pH levels and is a potential candidate for industrial application.
Authors:
Caroline Heath; Xiao Ping Hu; S Craig Cary; Donald Cowan
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-05-01
Journal Detail:
Title:  Applied and environmental microbiology     Volume:  75     ISSN:  1098-5336     ISO Abbreviation:  Appl. Environ. Microbiol.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-26     Completed Date:  2009-08-11     Revised Date:  2010-09-24    
Medline Journal Info:
Nlm Unique ID:  7605801     Medline TA:  Appl Environ Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4657-9     Citation Subset:  IM    
Affiliation:
Department of Biotechnology, University of the Western Cape, Cape Town, South Africa.
Data Bank Information
Bank Name/Acc. No.:
GENBANK/EU874395
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MeSH Terms
Descriptor/Qualifier:
Antarctic Regions
Burkholderia / genetics
DNA / genetics*,  isolation & purification*
Enzyme Stability
Escherichia coli / genetics
Esterases / genetics*
Gene Expression
Hydrogen-Ion Concentration
Molecular Sequence Data
Sequence Analysis, DNA
Sequence Homology, Amino Acid
Soil Microbiology*
Temperature
Chemical
Reg. No./Substance:
9007-49-2/DNA; EC 3.1.-/Esterases
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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