| Identification and molecular characterization of a S. agalactiae strain lacking the capsular locus. | |
| | |
MedLine Citation:
|
PMID: 21614482 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
During a national surveillance program on Group B streptococci (GBS) maternal carriage and neonatal infections, a GBS strain isolated from a pregnant woman's vagino-rectal swab was non typable by either serological or molecular methods. Further molecular characterization demonstrated that the strain lacked the entire capsular locus, possibly by a recombination event that excised a 14,1 Kbase pairs genomic fragment extending from the regulatory protein cpsX gene to the neuA gene. The natural loss of the capsular locus by GBS isolated from a human has never been described so far. Such an event, while possibly a dead-end from the evolutionary point of view, leaves a still able-to-colonize organism unrecognizable by the vaccines currently under development. |
| | |
Authors:
|
R Creti; M Imperi; M Pataracchia; G Alfarone; S Recchia; L Baldassarri |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-5-26 |
Journal Detail:
|
Title: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology Volume: - ISSN: 1435-4373 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-5-26 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8804297 Medline TA: Eur J Clin Microbiol Infect Dis Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Reparto di Malattie Batteriche Respiratorie e Sistemiche - Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161, Rome, Italy, roberta.creti@iss.it. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Stimulatory effect of low-level laser therapy on root development of rat molars: a preliminary study...
Next Document: Radionuclide concentrations in raw and purified phosphoric acids from Brazil and their processing wa...