| Identification of malic acid from yeast. | |
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MedLine Citation:
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PMID: 5640383 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Evidence indicated an accumulation of l-malic acid in the synthetic growth medium of both lysine auxotrophs and wild-type yeast. Malic acid was isolated from growth experiments and was identified by paper and column chromatography, by comparison of infrared spectra with authentic l-malic acid, as well as enzymatically, as a substrate of malic dehydrogenase. Malic acid was accumulated when glucose was used as a carbon source. This did not occur when sodium lactate was the carbon source. Malic, succinic, and citric acids, and a few other as yet unidentified organic acids, were accumulated in the culture supernatant fluid when yeast was grown in a chemically defined medium. The accumulation of these acids had no obvious relation to the pathway for lysine biosynthesis. |
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Authors:
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J K Bhattacharjee; M E Maragoudakis; M Strassman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of bacteriology Volume: 95 ISSN: 0021-9193 ISO Abbreviation: J. Bacteriol. Publication Date: 1968 Feb |
Date Detail:
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Created Date: 1968-05-03 Completed Date: 1968-05-03 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985120R Medline TA: J Bacteriol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 495-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetates
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metabolism Carbon Isotopes Chromatography Chromatography, Paper Citrates / analysis Glucose / metabolism Lactates / metabolism Lysine / metabolism Malates / analysis* Mutation Saccharomyces / analysis*, metabolism Succinates / analysis |
| Chemical | |
Reg. No./Substance:
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0/Acetates; 0/Carbon Isotopes; 0/Citrates; 0/Lactates; 0/Malates; 0/Succinates; 50-99-7/Glucose; 56-87-1/Lysine |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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