Document Detail

Identification of an immunoreactive non-proteinaleous component in Borrelia burgdorferi.
MedLine Citation:
PMID:  1722277     Owner:  NLM     Status:  MEDLINE    
Investigations of immunoblots using Borrelia burgdorferi antigen demonstrated that a band, migrating faster than the bromophenol blue front in sodium dodecyl sulfate-gel electrophoresis, reacted strongly with sera containing anti-Borrelia burgdorferi antibodies preferentially of the IgG class. Extraction of this antigenic component and chemical analyses showed that the substance was composed mainly of fatty acids and carbohydrates. Typical structures of classical lipooolysaccharides such as 3-deoxy-D-manno-2-octulosonic acid, hydroxy fatty acids or lipid A could not be detected.
H Eiffert; H Lotter; K Jarecki-Khan; R Thomssen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical microbiology and immunology     Volume:  180     ISSN:  0300-8584     ISO Abbreviation:  Med. Microbiol. Immunol.     Publication Date:  1991  
Date Detail:
Created Date:  1992-02-10     Completed Date:  1992-02-10     Revised Date:  2007-02-21    
Medline Journal Info:
Nlm Unique ID:  0314524     Medline TA:  Med Microbiol Immunol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  229-37     Citation Subset:  IM    
Department of Medical Microbiology, Georg-August-University, Göttingen, Federal Republic of Germany.
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MeSH Terms
Antibodies, Bacterial / immunology
Antigens, Bacterial / chemistry,  isolation & purification*
Borrelia burgdorferi Group / immunology*
Chromatography, Thin Layer
Cross Reactions / immunology
Electrophoresis, Polyacrylamide Gel
Enzyme-Linked Immunosorbent Assay
Epitopes / immunology
Lyme Disease / immunology
Reg. No./Substance:
0/Antibodies, Bacterial; 0/Antigens, Bacterial; 0/Epitopes

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