Document Detail


Identification of the human electrical impedance indifferent point: a surrogate for the volume indifferent point?
MedLine Citation:
PMID:  19672616     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Head-up tilt (HUT) redistributes approximately 700 mL of blood to the dependent regions. In a gravitational field, hydrostatic pressure is balanced against vascular compliance, resulting in a hydrostatic indifferent point (HIP) whose location should be coincident with an indifferent point for volume (VIP). Cardiac filling is determined by the hydrostatic gradient between the HIP/VIP and right atrium. We employed segmental impedance to examine blood volume redistribution during HUT and estimate the location of the VIP. During HUT, impedance increased in the chest and decreased in the lower abdomen, presumably due to blood volume shifts. Using a non-linear model to relate blood volume shifts to the hydrostatic gradient, we estimated the location of the electrical impedance indifferent point between the xyphoid process and iliac crest, at 64.5 +/- 2.6% of an individual's height. This method may provide a quantitative framework to assess the effects of blood volume distribution on tilt tolerance.
Authors:
Sara S Jarvis; James A Pawelczyk
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2009-08-12
Journal Detail:
Title:  European journal of applied physiology     Volume:  107     ISSN:  1439-6327     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-16     Completed Date:  2010-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  473-80     Citation Subset:  IM    
Affiliation:
Department of Kinesiology, The Pennsylvania State University, University Park, PA 16802, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Anthropometry / methods*
Biological Markers / analysis*
Blood Pressure / physiology
Blood Volume / physiology*
Body Composition / physiology*
Electric Impedance
Exercise Test
Female
Fluid Shifts / physiology*
Heart Rate / physiology
Humans
Male
Models, Biological
Posture / physiology
Young Adult
Grant Support
ID/Acronym/Agency:
MO1RR10732/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Biological Markers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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