Document Detail

Identification of differentially expressed genes in microarray data in a principal component space.
MedLine Citation:
PMID:  23539565     Owner:  NLM     Status:  Publisher    
Microarray experiments are often conducted in order to compare gene expression between two conditions. Tests to detected mean differential expression of genes between conditions are conducted applying correction for multiple testing. Seldom, relationships between gene expression and microarray conditions are investigated in a multivariate approach. Here we propose determining the relationship between genes and conditions using a Principal Component Analysis (PCA) space and classifying genes to one of two biological conditions based on their position relative to a direction on the PC space representing each condition.
Luis Ospina; Liliana López-Kleine
Related Documents :
6947965 - Alterations in the expression of ia antigens in f1 hybrid mice.
24995635 - Early warning signs of endocrine disruption in adult fish from the ingestion of polyeth...
24555715 - Dynamics of the chili pepper transcriptome during fruit development.
24397545 - Conserved co-ft regulons contribute to the photoperiod flowering control in soybean.
21236675 - Temporal repression of core circadian genes is mediated through early flowering 3 in ar...
22068705 - Establishment of a stable cell line coexpressing dengue virus-2 and green fluorescent p...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-19
Journal Detail:
Title:  SpringerPlus     Volume:  2     ISSN:  2193-1801     ISO Abbreviation:  Springerplus     Publication Date:  2013 Dec 
Date Detail:
Created Date:  2013-3-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101597967     Medline TA:  Springerplus     Country:  -    
Other Details:
Languages:  ENG     Pagination:  60     Citation Subset:  -    
Departamento de Estadística, Universidad Nacional de Colombia, Ciudad Universitaria carrera 30 con calle 45, edificio 404, Bogotá, Colombia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Vertical and Lateral Workplace Bullying in Nursing: Development of the Hospital Aggressive Behaviour...
Next Document:  Comment on "Nuclear genomic sequences reveal that polar bears are an old and distinct bear lineage".