Document Detail


Identification and determination of antihypertonics from the group of angiotensin-convertase inhibitors by densitometric method in comparition with HPLC method.
MedLine Citation:
PMID:  20369790     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Conditions have been elaborated for the identification of all the compounds belonging to the group of angiotensin convertase inhibitors: lisinopril, quinapril, ramipril, spirapril, moexipril, trandolapril, benazepril, cilazapril, fosinopril, captopril, enalapril, imidapril and zofenopril by thin-layer chromatography. The selected conditions were used to design the densitometric method for the content determination of the above mentioned compounds in substances and medicines. The statistical data obtained for the designed method indicate adequate accuracy and precision.
Authors:
Elzbieta Wyszomirska; Krystyna Czerwi?ska; Aleksander P Mazurek
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta poloniae pharmaceutica     Volume:  67     ISSN:  0001-6837     ISO Abbreviation:  Acta Pol Pharm     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-04-07     Completed Date:  2010-04-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985167R     Medline TA:  Acta Pol Pharm     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  137-43     Citation Subset:  IM    
Affiliation:
Department of Basic and Applied Pharmacy, National Medicines Institute, Warszawa, Poland. ewyszomirska@il.waw.pl
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MeSH Terms
Descriptor/Qualifier:
Angiotensin-Converting Enzyme Inhibitors / analysis*
Antihypertensive Agents / analysis*
Chromatography, High Pressure Liquid / methods*
Chromatography, Thin Layer / methods*
Densitometry / methods*
Chemical
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Antihypertensive Agents

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