Document Detail

Identification of T & B lymphocytes on skin sections from patients with lymphoproliferative disorders of the skin.
MedLine Citation:
PMID:  7003028     Owner:  NLM     Status:  MEDLINE    
The T & B lymphocytes in frozen sections of skin obtained from patients with various lympho-infiltrating disorders of the skin were identified using an immunofluorescent technique. Anti T-lymphocytes serum was used as a T marker and anti Ig GMA serum and HL-B alloantigens as B markers. The method confirmed to be efficient in preliminary experiments. Specimens were obtained from patients with lymphocytic infiltration of the skin (LIS), lymphadenosis benigna cutis (LBC), lymphoma cutis (LC) and mycosis fungoides (MF). In LIS and LBC the dominant cell was found to be the T lymphocyte, suggesting that a local immune reaction of the cell mediated type may play a role in their etiology.
M David; B Shohat; B Hazaz; E J Feuerman; H Joshua
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of investigative dermatology     Volume:  75     ISSN:  0022-202X     ISO Abbreviation:  J. Invest. Dermatol.     Publication Date:  1980 Dec 
Date Detail:
Created Date:  1981-02-24     Completed Date:  1981-02-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0426720     Medline TA:  J Invest Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  491-4     Citation Subset:  IM    
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MeSH Terms
B-Lymphocytes / immunology*
Fluorescent Antibody Technique
Lymphoma / immunology
Lymphoproliferative Disorders / immunology*
Mycosis Fungoides / immunology
Skin Diseases / immunology*
Skin Neoplasms / immunology
T-Lymphocytes / immunology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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