| Identification of a shine-through artifact in the trachea with (124)I PET/CT. | |
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MedLine Citation:
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PMID: 19470851 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The presence of (124)I in tissue near the trachea can cause a phenomenon that might be called shine-through. The effect is due to high-energy positrons that cross the air-filled trachea and annihilate at the opposite tracheal wall, incorrectly suggesting uptake at that location. METHODS: We investigated shine-through using (124)I, (68)Ga, and (18)F PET/CT scans of a neck phantom. Additionally, we evaluated (124)I studies of 29 patients with differentiated thyroid cancer who underwent imaging for postsurgical staging. RESULTS: In the phantom studies with a 0.1-mL (124)I source, the relative intensity of shine-through decreased from 7% to nearly zero when the thickness of the positron-stopping layer was increased from 0.3 to 3.85 mm. In patients, shine-through was observed in 5 of the 29 studies, with intensities between 0.7% and 14%. CONCLUSION: Shine-through appears rather common in differentiated thyroid cancer. Recognition is important for identification of real lesions, calculation of uptake, and dosimetry. |
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Authors:
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Sakar B Abdul-Fatah; Mariangela Zamburlini; Servé G E A Halders; Boudewijn Brans; Gerrit J J Teule; Gerrit J Kemerink |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of nuclear medicine : official publication, Society of Nuclear Medicine Volume: 50 ISSN: 0161-5505 ISO Abbreviation: J. Nucl. Med. Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-05-27 Completed Date: 2009-07-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0217410 Medline TA: J Nucl Med Country: United States |
Other Details:
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Languages: eng Pagination: 909-11 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Artifacts Humans Iodine Radioisotopes / diagnostic use* Phantoms, Imaging Positron-Emission Tomography / methods* Thyroid Neoplasms / radionuclide imaging Tomography, X-Ray Computed / methods* Trachea / radiography*, radionuclide imaging* |
| Chemical | |
Reg. No./Substance:
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0/Iodine Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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