Document Detail


Identification of Pneumocystis carinii in the lungs of infants dying of sudden infant death syndrome.
MedLine Citation:
PMID:  11303835     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Recently Pneumocystis carinii has been identified in a significant number of infants diagnosed as having died from sudden infant death syndrome (SIDS) in South America and Europe. METHODS: We examined lung sections of 79 infants who died with a diagnosis of SIDS in Rochester, NY, and Connecticut for the presence of P. carinii. RESULTS: Organisms with a characteristic silver stain appearance for P. carinii were identified in 14% of the lung sections. CONCLUSIONS: These data suggest that a possible link between some cases of SIDS and infection with P. carinii should be further evaluated and that infection of young infants may serve as an important reservoir for human P. carinii.
Authors:
D J Morgan; S L Vargas; M Reyes-Mugica; J N Walterspiel; W Carver; F Gigliotti
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  20     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-04-16     Completed Date:  2001-12-11     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  306-9     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of Rochester School of Medicine and Dentistry, NY 14642, USA.
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MeSH Terms
Descriptor/Qualifier:
Disease Reservoirs
Female
Humans
Immunohistochemistry
Infant
Lung / microbiology*,  pathology
Male
Pneumocystis / isolation & purification*
Pneumocystis Infections / complications*
Retrospective Studies
Sudden Infant Death / etiology*
Grant Support
ID/Acronym/Agency:
AI23302/AI/NIAID NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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