| Ideal AFROC and FROC observers. | |
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MedLine Citation:
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PMID: 20129845 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Detection of multiple lesions in images is a medically important task and free-response receiver operating characteristic (FROC) analyses and its variants, such as alternative FROC (AFROC) analyses, are commonly used to quantify performance in such tasks. However, ideal observers that optimize FROC or AFROC performance metrics have not yet been formulated in the general case. If available, such ideal observers may turn out to be valuable for imaging system optimization and in the design of computer aided diagnosis techniques for lesion detection in medical images. In this paper, we derive ideal AFROC and FROC observers. They are ideal in that they maximize, amongst all decision strategies, the area, or any partial area, under the associated AFROC or FROC curve. Calculation of observer performance for these ideal observers is computationally quite complex. We can reduce this complexity by considering forms of these observers that use false positive reports derived from signal-absent images only. We also consider a Bayes risk analysis for the multiple-signal detection task with an appropriate definition of costs. A general decision strategy that minimizes Bayes risk is derived. With particular cost constraints, this general decision strategy reduces to the decision strategy associated with the ideal AFROC or FROC observer. |
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Authors:
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Parmeshwar Khurd; Bin Liu; Gene Gindi |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: IEEE transactions on medical imaging Volume: 29 ISSN: 1558-254X ISO Abbreviation: IEEE Trans Med Imaging Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-04 Completed Date: 2010-05-04 Revised Date: 2012-04-24 |
Medline Journal Info:
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Nlm Unique ID: 8310780 Medline TA: IEEE Trans Med Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 375-86 Citation Subset: IM |
Affiliation:
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Siemens Corporate Research, Princeton, NJ 08540 USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Bayes Theorem Diagnostic Imaging / methods* Humans Image Interpretation, Computer-Assisted / methods* Models, Statistical* ROC Curve* |
| Grant Support | |
ID/Acronym/Agency:
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EB02629/EB/NIBIB NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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