Document Detail


Icterus Neonatorum in Near-Term and Term Infants: An overview.
MedLine Citation:
PMID:  22548133     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Neonatal jaundice is the yellowish discoloration of the skin and/or sclerae of newborn infants caused by tissue deposition of bilirubin. Physiological jaundice is mild, unconjugated (indirect-reacting) bilirubinaemia, and affects nearly all newborns. Physiological jaundice levels typically peak at 5 to 6 mg/dL (86 to 103 μmol/L) at 72 to 96 hours of age, and do not exceed 17 to 18 mg/dL (291-308 μmol/L). Levels may not peak until seven days of age in Asian infants, or in infants born at 35 to 37 weeks' gestation. Higher levels of unconjugated hyperbilirubinaemia are considered pathological and occur in a variety of conditions. The clinical features and management of unconjugated hyperbilirubinaemia in healthy near-term and term infants, as well as bilirubin toxicity and the prevention of kernicterus, are reviewed here. The pathogenesis and aetiology of this disorder are discussed separately.
Authors:
Rehan Ali; Shakeel Ahmed; Maqbool Qadir; Khalil Ahmad
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Publication Detail:
Type:  Journal Article     Date:  2012-04-09
Journal Detail:
Title:  Sultan Qaboos University medical journal     Volume:  12     ISSN:  2075-0528     ISO Abbreviation:  Sultan Qaboos Univ Med J     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-05-01     Completed Date:  2012-10-02     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101519915     Medline TA:  Sultan Qaboos Univ Med J     Country:  Oman    
Other Details:
Languages:  eng     Pagination:  153-60     Citation Subset:  -    
Affiliation:
Department of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
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