| Ictal asystole: a benign condition? | |
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MedLine Citation:
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PMID: 17900291 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ictal asystole (IA) has been implicated as a preventable cause of sudden unexplained death in epilepsy presumably provoked by a direct autonomic effect of the electrical stimulus on the heart. An electronic database search of patients with IA was performed comparing heart rate (HR) characteristics to a group of patients with vasovagal asystole. IA was seen in eight patients, all with temporal lobe epilepsy. No statistical difference was found in duration of asystole, bradycardia, and baseline HR characteristics except of a higher HR acceleration postasystole in the controls. None of the six patients with IA who underwent pacemaker implantation had recurrence of asystolic events during mean follow-up of 5 years. This study in a small group of patients suggests that the epileptic activation leading to IA is possibly mediated through a transient increase in vagal tone and not by a direct autonomic effect on the heart. |
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Authors:
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Stephan U Schuele; Adriana C Bermeo; Eduardo Locatelli; Richard C Burgess; Hans O Lüders |
Publication Detail:
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Type: Comparative Study; Journal Article Date: 2007-09-26 |
Journal Detail:
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Title: Epilepsia Volume: 49 ISSN: 0013-9580 ISO Abbreviation: Epilepsia Publication Date: 2008 Jan |
Date Detail:
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Created Date: 2008-01-10 Completed Date: 2008-02-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2983306R Medline TA: Epilepsia Country: United States |
Other Details:
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Languages: eng Pagination: 168-71 Citation Subset: IM |
Affiliation:
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Department of Neurology, Northwestern University, Chicago, IL, USA. s-schuele@northwestern.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bradycardia / diagnosis, epidemiology, prevention & control Comorbidity Databases as Topic / statistics & numerical data Death, Sudden, Cardiac / epidemiology Electrocardiography / methods, statistics & numerical data* Electroencephalography / statistics & numerical data Epilepsy / diagnosis*, epidemiology Follow-Up Studies Heart Arrest / diagnosis*, epidemiology, prevention & control Heart Rate / physiology Humans Male Middle Aged Pacemaker, Artificial Prognosis Recurrence / prevention & control Syncope, Vasovagal / diagnosis, epidemiology, prevention & control |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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