Document Detail

Ictal SPECT hyperperfusion reflects the activation of the symptomatogenic cortex in spontaneous and electrically-induced non-habitual focal epileptic seizures: correlation with subdural EEG recordings.
MedLine Citation:
PMID:  10937171     Owner:  NLM     Status:  MEDLINE    
We report a patient with left temporal lobe epilepsy and a left parietal angioma, in whom ictal SPECT showed hyperperfusion in a spontaneous and an electrically-induced, non-habitual focal seizure. A SPECT investigation during an habitual seizure originating in the left temporal lobe showed a left temporal hyperperfusion. Electrical stimulation of the parietal cortex adjacent to the location of a previously resected angioma using subdural electrodes resulted in a non-habitual seizure beginning with a unilateral somatosensory aura. Ictal SPECT of this seizure demonstrated contralateral central hyperperfusion. We conclude from our findings that ictal SPECT hyperperfusion reflects the activation of symptomatogenic cortex, which can be induced by both epileptic discharge and electrical stimulation.
S Arnold; S Noachtar; R Linke; K J Werhahn; T A Yousry; P A Winkler; K Tatsch
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Epileptic disorders : international epilepsy journal with videotape     Volume:  2     ISSN:  1294-9361     ISO Abbreviation:  Epileptic Disord     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-08-29     Completed Date:  2000-08-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100891853     Medline TA:  Epileptic Disord     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  41-4     Citation Subset:  IM    
Department of Neurology, University of Munich, Germany.
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MeSH Terms
Cerebral Cortex / blood supply*,  radionuclide imaging*
Cerebrovascular Circulation / physiology
Electric Stimulation
Epilepsies, Partial / physiopathology*,  radionuclide imaging*
Temporal Lobe / blood supply*,  radionuclide imaging*
Tomography, Emission-Computed, Single-Photon

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