Document Detail


Ichthyosis follicularis, alopecia and photophobia syndrome (IFAP): report of the first case with ocular and cutaneous manifestations in Brazil with a favorable response to treatment.
MedLine Citation:
PMID:  21670910     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ichthyosis follicular, alopecia, and photophobia (IFAP) syndrome is a rare disease, with possible X-linked mode of inheritance. The patient presented with ocular findings of photophobia, corneal scarring and erosions, superficial and deep corneal vascularization and myopia. He was treated with artificial tears and punctal occlusion with small improvement of photophobia. After three months using systemic retinoid (Acitretina) and posterior amniotic membrane transplantation in the left eye, there was a significant improvement of photophobia, corneal erosions and neuropsychomotor development.
Authors:
Luisa Moreira Höpker; Christie Graf Ribeiro; Luciane Moreira Oliveira; Ana Tereza Ramos Moreira
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Arquivos brasileiros de oftalmologia     Volume:  74     ISSN:  1678-2925     ISO Abbreviation:  Arq Bras Oftalmol     Publication Date:    2011 Jan-Feb
Date Detail:
Created Date:  2011-06-14     Completed Date:  2011-10-21     Revised Date:  2012-01-31    
Medline Journal Info:
Nlm Unique ID:  0400645     Medline TA:  Arq Bras Oftalmol     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  55-7     Citation Subset:  IM    
Affiliation:
Vision Center, Department of Ophthalmology and Otorrhinolaryngology, Hospital de Clínicas, Federal University of Paraná, Curitiba (PR), Brazil. luhopker2@yahoo.com.br
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MeSH Terms
Descriptor/Qualifier:
Acitretin / therapeutic use
Alopecia / diagnosis*,  drug therapy
Amnion / transplantation
Child, Preschool
Humans
Ichthyosis / diagnosis*,  drug therapy
Keratolytic Agents / therapeutic use
Male
Photophobia / diagnosis*,  surgery
Syndrome
Chemical
Reg. No./Substance:
0/Keratolytic Agents; 55079-83-9/Acitretin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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