Document Detail


Ichthyosiform sarcoidosis: A case report and review of the literature.
MedLine Citation:
PMID:  20804682     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sarcoidosis is a potentially life-threatening, multisystem, granulomatous disease that can present with cutaneous manifestations in patients. A rare cutaneous manifestation of this disease may resemble acquired ichthyosis. We report a 45-year-old woman with a several year history of dyspnea on exertion and panuveitis who presented to a county hospital with acquired lower extremity ichthyosis and a biopsy consistent with both acquired ichthyosis and noncaseating, granulomatous sarcoidosis. To our knowledge, this entity has been described in only 22 previous independent cases, with the present case being 1 of only 5 cases to rapidly progress to full systemic involvement. Furthermore, it is important to recognize the manifestations of sarcoidosis in the skin, because these may be the presenting signs of systemic illness.
Authors:
Brian P Kelley; Dornechia E George; Todd M LeLeux; Sylvia Hsu
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2010-08-15
Journal Detail:
Title:  Dermatology online journal     Volume:  16     ISSN:  1087-2108     ISO Abbreviation:  Dermatol. Online J.     Publication Date:  2010  
Date Detail:
Created Date:  2010-08-31     Completed Date:  2010-12-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610776     Medline TA:  Dermatol Online J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Baylor College of Medicine, Houston, Texas, USA.
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Antinuclear / blood
Biopsy
Dermatologic Agents / therapeutic use
Female
Granuloma / diagnosis,  drug therapy
Humans
Hypercalcemia / diagnosis
Ichthyosis / diagnosis*,  drug therapy,  pathology
Middle Aged
Panuveitis / drug therapy,  pathology
Parakeratosis / diagnosis,  drug therapy
Parathyroid Hormone / blood
Peptidyl-Dipeptidase A / blood
Prednisone / therapeutic use
Sarcoidosis / drug therapy,  pathology,  radiography*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antibodies, Antinuclear; 0/Dermatologic Agents; 0/Parathyroid Hormone; 53-03-2/Prednisone; EC 3.4.15.1/Peptidyl-Dipeptidase A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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