Document Detail

Iatrogenic tension pneumothorax in a rabbit (Oryctolagus cuniculus).
MedLine Citation:
PMID:  16050663     Owner:  NLM     Status:  MEDLINE    
The following case report describes a complication after accidental overinflation of the lungs in an anesthetized rabbit. After anesthetic induction, endotracheal intubation, and preparation for surgery, the rabbit's arterial oxygen saturation dropped. Positive-pressure ventilation was administered using manual compression on the reservoir bag. The rabbit's condition rapidly deteriorated, and emergency treatment including oxygen, anesthetic reversal, and thoracocentesis was initiated. The rabbit failed to respond to therapy. A focal, acute, alveolar, vascular, and pleural rupture of the right caudal medial lung lobe with secondary pulmonary tension pneumothorax and atelectasis was identified postmortem. The etiology and pathophysiology of the clinical signs are reviewed. Pulmonary pressure overload after manual or assisted ventilation and subsequent stress failure occurs when pulmonary pressures approach 40 mm Hg. Close attention to the animal's size, tidal volume, and potentially altered pulmonary elasticity from pre-existing lung disease may help reduce the incidence of failure. Successful therapy of iatrogenic pneumothorax may necessitate both medical and surgical intervention.
Jon D Reuter; Krista J Fowles; Gordon A Terwilliger; Carmen J Booth
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article    
Journal Detail:
Title:  Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science     Volume:  44     ISSN:  1060-0558     ISO Abbreviation:  Contemp Top Lab Anim Sci     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-07-29     Completed Date:  2005-09-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9204153     Medline TA:  Contemp Top Lab Anim Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  22-5     Citation Subset:  IM    
Section of Comparative Medicine, Yale University School of Medicine, P.O. Box 208016, New Haven, Connecticut 06520-8016, USA.
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MeSH Terms
Fatal Outcome
Iatrogenic Disease / veterinary*
Lung / pathology
Pneumothorax / etiology,  pathology*,  veterinary*
Radiography, Thoracic / veterinary
Respiration, Artificial / adverse effects*

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