Document Detail

Iatrogenic neonatal hypertrophic cardiomyopathy.
MedLine Citation:
PMID:  8660453     Owner:  NLM     Status:  MEDLINE    
Transient hypertrophic cardiomyopathy is a rare sequela of both glucocorticoid and insulin excess. We report two ELBW infants who developed hypertrophic cardiomyopathy as an iatrogenic complication of the concurrent therapeutic administration of a glucocorticoid and insulin. In both cases the hypertrophic cardiomyopathy resolved completely on cessation of therapy. We advise caution when using this therapeutic combination and stress the need for regular echocardiography.
A W Gill; G Warner; L Bull
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric cardiology     Volume:  17     ISSN:  0172-0643     ISO Abbreviation:  Pediatr Cardiol     Publication Date:    1996 Sep-Oct
Date Detail:
Created Date:  1996-09-11     Completed Date:  1996-09-11     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  335-9     Citation Subset:  IM    
Department of Neonatology, John Hunter Hospital, Lookout Road, New Lambton Heights, N.S.W. 2305, Australia.
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MeSH Terms
Cardiomyopathy, Hypertrophic / chemically induced*,  ultrasonography
Dexamethasone / adverse effects*
Drug Therapy, Combination
Glucocorticoids / adverse effects*
Hypoglycemic Agents / adverse effects*
Iatrogenic Disease*
Infant, Newborn
Insulin / adverse effects*
Reg. No./Substance:
0/Glucocorticoids; 0/Hypoglycemic Agents; 11061-68-0/Insulin; 50-02-2/Dexamethasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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