Document Detail


Iatrogenic neonatal hypertrophic cardiomyopathy.
MedLine Citation:
PMID:  8660453     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Transient hypertrophic cardiomyopathy is a rare sequela of both glucocorticoid and insulin excess. We report two ELBW infants who developed hypertrophic cardiomyopathy as an iatrogenic complication of the concurrent therapeutic administration of a glucocorticoid and insulin. In both cases the hypertrophic cardiomyopathy resolved completely on cessation of therapy. We advise caution when using this therapeutic combination and stress the need for regular echocardiography.
Authors:
A W Gill; G Warner; L Bull
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric cardiology     Volume:  17     ISSN:  0172-0643     ISO Abbreviation:  Pediatr Cardiol     Publication Date:    1996 Sep-Oct
Date Detail:
Created Date:  1996-09-11     Completed Date:  1996-09-11     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  335-9     Citation Subset:  IM    
Affiliation:
Department of Neonatology, John Hunter Hospital, Lookout Road, New Lambton Heights, N.S.W. 2305, Australia.
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MeSH Terms
Descriptor/Qualifier:
Cardiomyopathy, Hypertrophic / chemically induced*,  ultrasonography
Dexamethasone / adverse effects*
Drug Therapy, Combination
Echocardiography
Female
Glucocorticoids / adverse effects*
Humans
Hypoglycemic Agents / adverse effects*
Iatrogenic Disease*
Infant
Infant, Newborn
Insulin / adverse effects*
Male
Chemical
Reg. No./Substance:
0/Glucocorticoids; 0/Hypoglycemic Agents; 11061-68-0/Insulin; 50-02-2/Dexamethasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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