| Iatrogenic myocardial edema with potassium cardioplegia. | |
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MedLine Citation:
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PMID: 459529 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Postischemic myocardial edema depresses left ventricular function and coronary perfusion. Pharmacologic cardioplegia is being used increasingly to enhance myocardial protection during cardiac operations. In the present study we varied the colloid osmotic and osmotic pressures and the infusion pressures of four cardioplegic solutions to determine their respective roles in producing or preventing myocardial edema in a nonischemic setting. We found that myocardial edema during potassium cardioplegia (1) is independent of infusion pressures, (2) is caused by isosmotic crystalloid solutions, (3) is worsened by hyposmolar crystalloid solutions, (4) is avoided by the addition of colloid, and (5) is avoided if the solution is made hyperosmotic with the addition of mannitol. |
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Authors:
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R P Foglia; D L Steed; D M Follette; E DeLand; G D Buckberg |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of thoracic and cardiovascular surgery Volume: 78 ISSN: 0022-5223 ISO Abbreviation: J. Thorac. Cardiovasc. Surg. Publication Date: 1979 Aug |
Date Detail:
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Created Date: 1979-09-25 Completed Date: 1979-09-25 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376343 Medline TA: J Thorac Cardiovasc Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 217-22 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Water / metabolism Dogs Edema, Cardiac / chemically induced*, physiopathology Heart Arrest, Induced* Heart Failure / chemically induced* Iatrogenic Disease Myocardial Contraction Myocardium / metabolism Osmotic Pressure Potassium / administration & dosage, toxicity* Solutions |
| Chemical | |
Reg. No./Substance:
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0/Solutions; 7440-09-7/Potassium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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