| Iatrogenic hyperammonemia after anorexia. | |
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MedLine Citation:
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PMID: 20212188 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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High-protein dietary supplements were started for 2 patients, who had a period of anorexia before hospital admission but no history of liver disease. Subsequent altered mental status with ataxia developed in both patients. After excluding other causes, hyperammonemia was noted, while liver function test results remained normal. Removal of the high-protein dietary supplements led to reversal of symptoms and normalization of the ammonia level. With the ubiquity of nutrition supplement use outside of liver failure, SHAKE (supplement-associated hyperammonemia after c[k]achetic episode) syndrome may be commonplace in modern hospitals. |
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Authors:
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Emily Welsh; Jan Kucera; Michael D Perloff |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Archives of internal medicine Volume: 170 ISSN: 1538-3679 ISO Abbreviation: Arch. Intern. Med. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-09 Completed Date: 2010-04-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372440 Medline TA: Arch Intern Med Country: United States |
Other Details:
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Languages: eng Pagination: 486-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Neurology, Boston University School of Medicine, MA 02118, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anorexia
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complications* Brain Diseases, Metabolic / complications*, etiology* Cognition Disorders / etiology* Dietary Proteins / administration & dosage*, adverse effects* Female Humans Hyperammonemia / etiology* Lactulose / administration & dosage Liver Function Tests Male Middle Aged Nutritional Status Weight Gain Weight Loss |
| Chemical | |
Reg. No./Substance:
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0/Dietary Proteins; 4618-18-2/Lactulose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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