Document Detail

Iatrogenic damage in the neonatal period.
MedLine Citation:
PMID:  15251147     Owner:  NLM     Status:  MEDLINE    
Iatrogenic damage from a therapeutic procedure in the neonatal period can have serious consequences. Although most side effects are minor, some may result in a major handicap or death of the infant. The development of new therapeutic strategies may result in not previously observed combinations of pathology. This review focuses on iatrogenic damage occurring in several organs and after several different therapeutic interventions. Special attention is given to pulmonary and gastrointestinal damage and iatrogenic damage as a result of systemic treatments. Valuable information and early detection of serious side effects is only possible when the pathologist is very well informed about the therapeutic interventions used, all medical devices are left in situ and a thorough autopsy is performed as completely as is permitted. However, the decline in autopsy rates could make it more difficult to determine the incidence of iatrogenic lesions.
Peter G J Nikkels
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in neonatology : SN     Volume:  9     ISSN:  1084-2756     ISO Abbreviation:  Semin Neonatol     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-07-14     Completed Date:  2004-10-26     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9606001     Medline TA:  Semin Neonatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  303-10     Citation Subset:  IM    
Copyright Information:
Copyright 2004 Elsevier Ltd.
Department of Pathology, University Medical Centre Utrecht, P.O. Box 85500, 3508 GA Utrecht, The Netherlands.
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MeSH Terms
Anti-Bacterial Agents / adverse effects,  therapeutic use
Catheters, Indwelling / adverse effects
Diuretics / adverse effects,  therapeutic use
Eye / pathology
Gastrointestinal Tract / pathology
Iatrogenic Disease* / epidemiology
Infant, Newborn
Infant, Newborn, Diseases / epidemiology,  etiology*,  pathology
Lung / pathology
Prostaglandins / adverse effects,  therapeutic use
Steroids / adverse effects,  therapeutic use
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Diuretics; 0/Prostaglandins; 0/Steroids

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