Document Detail

Iatrogenic autoimmune progesterone dermatitis caused by 17alpha-hydroxyprogesterone caproate for preterm labor prevention.
MedLine Citation:
PMID:  22272488     Owner:  NLM     Status:  MEDLINE    
Preterm birth is the leading cause of perinatal morbidity and mortality in otherwise healthy infants, and the rate of pregnancies complicated by a premature delivery continues to rise. Subsequently, attempts have been made to reduce this rate by using progesterone supplementation during pregnancy. 17alpha-Hydroxyprogesterone caproate (17P), a metabolite of progesterone, also has been used as supplementation during pregnancy to prevent preterm births. We report a case of iatrogenic autoimmune progesterone dermatitis (APD) in a pregnant woman who received 17P therapy. Due to the increased use of 17P, our case could represent an increasingly prevalent entity that dermatologists and obstetricians should recognize. In this article, we discuss our findings and provide a basic review of APD.
Justin P Bandino; John Thoppil; J Scott Kennedy; Chad M Hivnor
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cutis     Volume:  88     ISSN:  0011-4162     ISO Abbreviation:  Cutis     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2012-01-25     Completed Date:  2012-03-01     Revised Date:  2013-09-12    
Medline Journal Info:
Nlm Unique ID:  0006440     Medline TA:  Cutis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  241-3     Citation Subset:  IM    
San Antonio Military Medical Center, Texas, USA.
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MeSH Terms
Autoimmune Diseases / diagnosis*
Fluorescent Antibody Technique, Indirect
Hydroxyprogesterones / administration & dosage,  adverse effects*
Iatrogenic Disease
Obstetric Labor, Premature / prevention & control*
Progesterone / adverse effects
Progestins / administration & dosage,  adverse effects*
Reg. No./Substance:
0/Hydroxyprogesterones; 0/Progestins; 57-83-0/Progesterone; 630-56-8/17-alpha-hydroxy-progesterone caproate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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