Document Detail

IVM--the first choice for IVF in Italy.
MedLine Citation:
PMID:  16895627     Owner:  NLM     Status:  MEDLINE    
In March 2004, a new law was introduced in Italy to regulate assisted reproduction; at present it is impossible to use more than a maximum of three oocytes per IVF cycle, nor can embryos or prezygotes (2PN cells) be selected or cryopreserved. The prohibitions introduced by the new law have, on the one hand, reduced the expectations of success of current techniques and, on the other hand, stimulated clinicians and embryologists to work on new therapeutic strategies so as to offer the highest chances of success with the lowest risks. In-vitro maturation (IVM) of oocytes fits very well with these new requirements: ovarian stimulation is avoided and the handling of spare oocytes is facilitated. The IVM protocol is an intriguing alternative to conventional IVF techniques, since it removes the side-effects of drug stimulation, especially ovarian hyperstimulation syndrome, and it also reduces the costs of the entire procedure, both in terms of 'time consumption' and 'patient/society costs for drugs'. In the authors' IVF centre the IVM technique has been used for more than a year, with significant success in terms of maturation and fertilization rates, percentage of embryo transfers, number of pregnancies and, finally, healthy babies born.
M B Dal Canto; M Mignini Renzini; F Brambillasca; H Cepparo; R Comi; A Villa; G Rangoni; M Mastrolilli; M Crippa; E de Ponti; H I Nielsen; R Fadini
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  13     ISSN:  1472-6483     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-09     Completed Date:  2006-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  159-65     Citation Subset:  IM    
BIOGENESI Reproductive Medicine Centre, Istituti Clinici Zucchi, V. Zucchi, 24-Monza, Italy.
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MeSH Terms
Embryo Transfer
Fertilization in Vitro / economics,  legislation & jurisprudence,  methods*
Infertility, Female / therapy*
Oocytes / growth & development
Ovulation Induction / adverse effects,  economics
Pregnancy Rate
Pregnancy, Multiple / statistics & numerical data

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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