| IVIG treatment for VZV-related acute inflammatory polyneuropathy in a child. | |
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MedLine Citation:
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PMID: 22814982 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Acute inflammatory polyneuropathy is an inflammatory demyelinating disease triggered by an autoimmune mechanism. It follows an infection or an immunisation after a free interval of 2-30 days. We report a case of a 14-year-old boy who develops an acute rapidly progressive paraplegia, urine incontinence and positive Lasegue a week after a characteristic chickenpox rash. Spinal MRI showed diffuse thickening and leptomeningeal enhancement of cauda equina nerve roots. Intravenous immunoglobulins were given and yielded a dramatic clinical and radiological improvement. The patient was discharged without any clinical problems 1 month after the onset of symptoms. We performed a review of the literature, discussing the different forms of varicella-zoster virus-related central and peripheral nervous system complications and management strategies for acute postinfectious encephalomyelitis/radiculitis. |
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Authors:
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Danilo Buonsenso; Benedetta Focarelli; Piero Valentini; Roberta Onesimo |
Publication Detail:
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Type: Journal Article Date: 2012-07-19 |
Journal Detail:
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Title: BMJ case reports Volume: 2012 ISSN: 1757-790X ISO Abbreviation: BMJ Case Rep Publication Date: 2012 |
Date Detail:
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Created Date: 2012-07-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101526291 Medline TA: BMJ Case Rep Country: England |
Other Details:
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Languages: eng Pagination: - Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Pediatric Infectious Diseases Unit, Catholic University of the Sacred Heart, Rome, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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